Fluoroquinolones are antibiotics that are commonly used to treat a variety of illnesses such as respiratory and urinary tract infections, with ciprofloxacin and delafloxacin being the most common. However, there is the issue that fluoroquinolones increase the risk for tendinopathy. This means it is important that the drug history of anyone with a tendon issue is evaluated.

Fortunately this risk only appears to be associated with the first and second generation fluoroquinolones with the third and fourth generation drugs not being associated with an increased risk of tendinopathy.